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Virginia Tech Cancer Research Alliance

Boundless Innovation to Stop Cancer

The Virginia Tech Cancer Research Alliance harnesses the intellectual power of more than 30 research teams in fields spanning microbiology, veterinary oncology, neuroscience, psychology, and engineering

DNA molecules

The Virginia Tech Cancer Research Alliance will host its first retreat on Jan. 14, 2022, 8 a.m. to 5 p.m., at the Fralin Biomedical Research Institute at VTC in Roanoke, Virginia. Register here to attend. Include an abstract to be considered for a poster presentation. 

The Virginia Tech Cancer Research Alliance is cross-disciplinary team of cancer scientists who are introducing novel preventions, diagnostics, and therapeutics for a variety of cancers. The initiative, led by Virginia Tech's Vice President for Health Sciences and Technology, Michael Friedlander, Ph.D., was launched in 2019 to elevate cancer research projects across the university and encourage new collaborations.

From building microchips that detect epigenetic modifications in the mechanisms underlying cancer, to modulating the environmental factors and human behaviors that influence a patient’s risk, Virginia Tech researchers explore the basic biology, risk factors, and clinical interventions to reduce morbidity and mortality in humans and pets. 

Virginia Tech Cancer Research Alliance faculty members from across the university hold 22 active cancer research awards from the National Cancer Institute, part of the National Institutes of Health, and published 47 cancer discoveries in 2020 alone.

 

The Alliance strives to position Virginia Tech to become an international leader in cancer research - creating leading-edge diagnostics, preventions, and treatments for the future.

All Virginia Tech faculty members who study aspects of cancer are invited to join the Virginia Tech Cancer Research Alliance to spur new research collaborations and elevate the university's concerted efforts to end cancer.

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  3. Graybill PM, Jana A, Kapania RK, Nain AS, Davalos RV. Single Cell Forces after Electroporation. ACS Nano. 2021 Feb 23;15(2):2554-2568. doi: 10.1021/acsnano.0c07020. Epub 2020 Nov 25. PMID: 33236888.
  4. Beitel-White N, Lorenzo MF, Zhao Y, Brock RM, Coutermarsh-Ott S, Allen IC, Manuchehrabadi N, Davalos RV. Multi-Tissue Analysis on the Impact of Electroporation on Electrical and Thermal Properties. IEEE Trans Biomed Eng. 2021 Mar;68(3):771-782. doi: 10.1109/TBME.2020.3013572. Epub 2021 Feb 18. PMID: 32746081.
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  1. Nagai-Singer MA, Allen IC, et al. 2020. "Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model." Journal of Visualized Experiments.
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  3. Brock RM, Beitel-White N, Coutermarsh-Ott S, Grider DJ, Lorenzo MF, Ringel-Scaia VM, Manuchehrabadi N, Martin RCG, Davalos RV, Allen IC. Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing. Front Oncol. 2020 May 22;10:843. doi: 10.3389/fonc.2020.00843. PMID: 32528898; PMCID: PMC7257557.
  4. Hendricks AD, Vlaisavljevich E, Allen IC, et al. 2020. Determing the Mechanism of the Immune Response to Histotipsy Ablation of Pancreatic Cancer. Journal of Immunology.
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  6. Brock R, Davalos RV, Allen IC, et al. 2020. "Irreversible electroporation can alter immune cell composition and enhance antigen presentation potential in pancreatic cancer." Journal of Immunology.
  7. Brock R, Davalos RV, Allen IC, et al. 2020. "Abstract: PR8 Irreversible electroporation is an effective tumor-ablation strategy that induces immunologic cell death and promotes systemic antitumor immunity." Cancer Immunology Research.
  8. Partridge B, Allen IC, Davalos RV, Dervisis NG, et al. 2020. "High-Frequency Irreversible Electroporation for Treatment of Primary Liver Cancer: A Proof-of-Principle Study in Canine Hepatocellular Carcinoma." Journal of Vascular and Interventional Radiology.
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  14. Liu H, Yao C, Zhao Y, Chen X, Dong S, Wang L, Davalos RV. In Vitro Experimental and Numerical Studies on the Preferential Ablation of Chemo-Resistant Tumor Cells Induced by High-Voltage Nanosecond Pulsed Electric Fields. IEEE Trans Biomed Eng. 2020 Nov 24;PP. doi: 10.1109/TBME.2020.3040337. Epub ahead of print. PMID: 33232222.
  15. Zhao Y, Zheng S, Beitel-White N, Liu H, Yao C, Davalos RV. Development of a Multi-Pulse Conductivity Model for Liver Tissue Treated With Pulsed Electric Fields. Front Bioeng Biotechnol. 2020 May 19;8:396. doi: 10.3389/fbioe.2020.00396. PMID: 32509742; PMCID: PMC7248411.
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  8. Douglas TA, Alinezhadbalalami N, Balani N, Schmelz EM, Davalos RV. Separation of Macrophages and Fibroblasts Using Contactless Dielectrophoresis and a Novel ImageJ Macro. Bioelectricity. 2019 Mar 1;1(1):49-55. doi: 10.1089/bioe.2018.0004. Epub 2019 Mar 18. PMID: 32292890; PMCID: PMC6524653.
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  12. Ivey JW, Wasson EM, Alinezhadbalalami N, Kanitkar A, Debinski W, Sheng Z, Davalos RV, Verbridge SS. Characterization of Ablation Thresholds for 3D-Cultured Patient-Derived Glioma Stem Cells in Response to High-Frequency Irreversible Electroporation. Research (Wash D C). 2019 Apr 28;2019:8081315. doi: 10.34133/2019/8081315. PMID: 31549086; PMCID: PMC6750069.
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The Virginia Tech Cancer Research Alliance was formed in 2019 under the Office of the Vice President for Health Sciences and Technology, Michael Friedlander, Ph.D. It is co-directed by Dr. Dervisis, Dr. Finkielstein, Dr. Munson, and Dr. Slade:

 

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